منابع مشابه
When defense turns into attack
The APOBEC3 cytidine deaminases play an important role in innate immunity but have also emerged as mediators of somatic mutations in human cancer. We recently reported a high incidence of APOBEC-mediated driver mutations in human papillomavirus-associated cancer, suggesting a key role for these enzymes in the development of such tumors.
متن کاملWhen Gaze Turns into Grasp
Previous research has provided evidence for a neural system underlying the observation of another person's hand actions. Is the neural system involved in this capacity also important in inferring another person's motor intentions toward an object from their eye gaze? In real-life situations, humans use eye movements to catch and direct the attention of others, often without any accompanying han...
متن کاملWhen strength turns into disease: acne fulminans in a bodybuilder*
A 31-year-old male visited our hospital seeking dermato-logical care. He had been bodybuilding for a long time and had recently initiated a strict preparation program for a contest. To this end, he took intramuscular testosterone injections on three occasions , developing severe acneiform lesions. The course was gradual but progressive, leading to limitations in his daily activities, with arthr...
متن کاملWhen Sweet Turns Salty
SEE PAGE 804 O ne of the most challenging aspects of obesity is its link to “metabolic syndrome,” when abdominal obesity is accompanied by high fasting blood glucose, low levels of high-density lipoprotein cholesterol, high levels of triglycerides, and elevated blood pressure. With rising obesity rates, metabolic syndrome is likely to become more common in the years ahead (1). Although progress...
متن کاملWhen splicing turns bad.
RNA splicing, the process that removes introns from pre-mRNA and links exons together to generate the fully mature messenger RNA (mRNA), is a complicated and highly regulated process. Splicing is catalyzed by the spliceosome, a large RNA-protein complex composed of several small nuclear ribonucleoprotein complexes (snRNPs) that each have a specific task during splicing. Correct splicing is impo...
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ژورنال
عنوان ژورنال: Molecular & Cellular Oncology
سال: 2014
ISSN: 2372-3556
DOI: 10.4161/mco.29914